The book on the topic is at http://worrydream.com/refs/Hamming-TheArtOfDoingScienceAndEn... .

I read Hamming's "You and Your Research" some years back, and recall that it was quite appropriate. See http://www.cs.utexas.edu/~dahlin/bookshelf/hamming.html for the text. It's the penultimate lecture in the video series.