I hanen't touched Django in some time, but something like this should work:

    from django.db import models
    from django.db import connection

    class MyModel(models.Model):
        name = models.CharField(max_length=255)

        class Meta:
            app_label = 'myapp'


    with connection.schema_editor() as schema_editor:
        schema_editor.create_model(MyModel)

    # from django.core.management import call_command
    # call_command('makemigrations', 'myapp')
    # call_command('migrate', 'myapp')

A lot could be said about it, but the first thing that comes to mind is that not every application uses a db.

And not every application that uses a db needs an ORM.

You probably can build an ORM into the single file. But I'm not saying every application should be developed as a single file forever. I just like that you can start with one and expand later.

Then you don't need django, flask and fast API already does all that withing a single file.

What makes django useful is the admin, auth, session and so on that are all built around the ORM.

You never know into what a project will develop. So it is nice to know you can expand it into anything, even when you start simple.