Very interesting! Two-photon pumping of traditional lasers with only 2 states would require absurd energy densities, but I guess the combination of a strong quadrupole coupling and long state decay times makes it feasible for a nuclear laser.
Still not clear what it would be useful for outside of clocks, but definitely a very cool physics project, and I'm sure someone would find other uses eventually.
"Solid-state 229 Th nuclear laser with two-photon pumping"
http://web.mit.edu/pcappell/www/pubs/Xu23a.pdf [pdf]