I'm not saying that people should kill others or themselves because of the amounts of money involved here, and I'm not entirely sure what the minimum threshold is for financial crimes where that becomes an (grim and unfortunate) side effect, but when we're discussing the largest fraud in history it's definitely on that scale. Even though he stole money, the human cost of that is beyond just fractured careers and relationships, undoubtedly because of how humans behave people almost certainly lost their entire lives due to the continuing effects caused only by this crime. That cost in human life should be taken into account here, even if it shouldn't have had that kind of cost.