The interest on the loan is $1B a year. Twitter’s revenue in 2021 was $6B. Can he pay the interest back? Sure. Is he going to have 1B in liquid capital every year? Harder.
Does he ever recoup the cost of buying Twitter at that rate? outlook doesn’t look good.
Just because he’s super-rich doesn’t mean he’s immune to bad decisions. Becoming rich and staying rich are two different skill sets. Many a fortune has been squandered by people pursuing bad ideas.