Possibly, but I would more readily attribute it to COVID-specific causes. All of my friends and coworkers who have kids have been dealing with remote schooling, and they've all been noticeably more stressed because of it. My partner who is an extrovert suddenly had far less access to human interaction, and they've been visibly happier day to day in the more recent months despite work not being any less stressful in large part due to seeing more people in person. Zoom just didn't do it for them.
Myself too. It wasn't the remoteness that bugged me. I live less than 10 minutes from my office, so it's not like the lack of a commute even factored in. And I've worked with geographically distributed teams my whole career. It was the simultaneous social isolation outside of work and having just moved to a new location where I didn't have an established support network, taking away my normal channels for dealing with stress.
IME this Pandemic-from-home season isn't like the usual WFH where one has non-work social outlets. So it could be remoteness, more COVID-related, other factors, or a combination.
Maybe all that is caused by remoteness?