the reverse was actually possible: there were PC compatible expansion cards for the amiga [1]. The issue is that they were very expensive and 8088 only.
Yes, those PC Card addons for Mac/Amiga/etc are endlessly fascinating to me. But with the benefit of hindsight, the crucial factor wasn't just being able to run DOS applications on your fancy propriety computer, it was riding the PC Compatible rocketship as it blasted off. Creative Labs and 3Com and Tseng and many others showed that there was more value in manufacturing a popular expansion in the massive PC world than in owning your own closed platform bow-to-stern.
- in the late 80s, Commodore ports AmigaOS to 386
- re-engineers Original Chipset as an ISA card
- OCS combines VGA output and multimedia (no SoundBlaster needed)
- offers AmigaOS to everyone, but it requires their ISA card to run
- runs DOS apps in Virtual 8086 mode, in desktop windows or full-screen