I was recently struggling whether commit my new TODO list to WorkFlowy and OrgMode, and I made a small comparison:

  Org Mode
  + You get full editing power of Emacs
  + Lots and lots of features (custom TODOs, calendars, hyperlinks,
    generating documents, ...) that are hidden and doesn't distract
    people who are not aware of them.
  + It IS actively developed all the time :).
  - Not really portable - requires Emacs for nice look&feel,
    although .org files are just text files, so one MIGHT be able
    to work with them.

  WorkFlowy
  + Webapp, so it's extremely portable.
  + Web-based, so it's always synchronized :).
  + Ability to zoom-in on a selected part of your list is much better
    done than the Org-Mode one (at least the "C-x n s" I know about).
  - Bad editing shortcuts and lack of general text editing capabilities
    I'm used to (ie. CTRL+arrows doesn't move around text by jumping words).

I finally chose Org Mode (don't need to synchronize that list, and I do need the editing powers), but I also have a lot of stuff on WorkFlowy that I need to have synchronized between work, home, and whereever I go.