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Yes, the story was something like Google hadn’t rebuilt their index for something like 8 months if I recall correctly


Does anyone else remember the Mac app “gravitation” that did this? Brings back memories


Check out https://mynucleus.com -- we do whole-genome DNA sequencing from a cheek swab for about $500 (use code savraj10 for 10% off), so no blood drawn as in this example. We also give you your risks for over 2k diseases and, if your partner does the test, predict outcomes for your future kids. Alexis is one of our investors and we have a big announcement coming next week! We also allow download of all raw data and are SOC2 + HIPAA compliant.


What’s stopping a similar crisis that 23andMe customers faced where their genetic data along with their identifying information getting sold to the highest bidder if you ever become insolvent?

Considering how big a deal that was at the time, and how strong a differentiator it would be, it’s notable how absent from the homepage. It’s nice that Nucleus claims not to sell the data, but 23andMe had similar claims, it wasn’t strong enough to prevent genetic data from being transferred if they were to be acquired.

This has always been something I’ve been interested in but so far no company handles privacy concerns of data that’s so deeply fundamentally personal and private in a satisfactory way, and I’m especially apprehensive post-23andMe.

Taking a dice roll on Nucleus not just pulling another 23andMe seems not worth the ~$3000 saving you claim to be offering.


> What’s stopping a similar crisis that 23andMe customers faced where their genetic data along with their identifying information getting sold to the highest bidder if you ever become insolvent?

Nucleus employee here. Nucleus is a medical provider that is providing a medical service and is regulated by medical laws, which extend even through bankruptcy or acquisition. Whereas 23andMe was essentially an entertainment company and was regulated as such, which is what enabled that unfortunate situation to occur.


23andMe’s data isn’t a whole genome. It’s a lot less useful diagnostically, and that’s why it isn’t that valuable.


The problem for me is not getting my DNA sequenced but not having to trust a third party with my genetic information. As wirtten in the article, they only achieved a 13% coverage (even less if because you have to assume that not all base calls are correct), which is not useful for any sort of genetic analysis. So the title is really misleading.


Amazing. I remember when something like this was a massive cost, if even accessible to the layperson. Now it's ~$500? Godspeed.


What coverage does your sequencing provide?


You're saying that having Alexis Ohanian as your investor makes you more trustworthy? :]


Do you accept monero?


Game genie was only on regular Nintendo. Those other modes on goldeneye were an Easter egg built into the game, iirc


You're right that N64 did not have Game Genie (Super Nintendo and Sega Genesis also did), but N64 did have Gameshark, which was the spiritual successor to Game Genie (along with Action Replay). There is a project (https://github.com/JCR64/GoldenEye-007-N64-Gun-Game) that adds games to Goldeneye via Gameshark


Because it works wonders on non-technical people


clickpass, YC s07


No pm2.5?


Not yet. Unfortunately, these are usually quite big, and we didn't want to sacrifice the portability. But you can add a PM sensor through the extension port. We'll document this in our upcoming manual.

A fellow Crowd Supply project, Polverine[1], uses a new Bosch sensor that is very small. If we do a refresh of the device, we'll certainly look into adding it.

[1]: https://www.crowdsupply.com/blackiot/polverine


IMO, PM2.5 sensors are essential nowadays. What's the point of a device without one? Especially for $229. I can get a chinese thingy like qingping for ~$115 with PM2.5 and other stuff.


SEVAK13,,"SEVAK = SERVANT, 13 = THERA = YOUR, IN PUNJABI THIS MEANS ""GOD, I AM YOUR SERVANT.""","13, GANG REFERENCE",N

Yes, Sevak is servant and the number 13 in Punjabi is "tera" which also means "yours".

Unfortunately in California the number 13 is a GANG REFERENCE. lol. Probably a free-speech argument to be made here?


As far as I can tell, no money goes to improving transit between New Jersey and New York


I think that was because NJ rejected the revenue deal as they pushed back against congestion pricing.

For example: https://nyc.streetsblog.org/2024/12/18/nj-refusing-generous-...

My hope is this will change as NJ accepts the outcome and benefits from it too.


Perhaps that will change when the price goes up in a few years, assuming Phil Murphy gives up on frivolous lawsuits and asking the president to stick his nose in.


The price is going up this year to sprint back to $20 which is what it should cost if not for all the whining from non-residents of Manhattan.


I have had this exact same idea, it’s a good one. We all hate ads, and muting the audio is all we really need!


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