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We only use IPSC. Details of the protocol to turn them into neurons and glial cells are described in our publication. https://www.frontiersin.org/journals/artificial-intelligence...


I am not sure lack of immune system is our main concern so far at FinalSpark. I believe it has more to do with the side effects of physical contacts of neurons (and glial cells) with not fully biocompatible materials like the electrodes.


I am one of co-founders of this company. Many of the questions asked here are answered in our recent publication: https://www.frontiersin.org/journals/artificial-intelligence...

I will be happy to try to answer any other questions!


How confident are you that these brain organoids are incapable of qualia and thus suffering?


Username relevant.-

PS. Also, while congratulating the company, I also wanted to appreciate and second the question ...


We have no information on this topic. Consider that at this time we have the number of neurons equivalent to a larva fly.


Flies have demonstrated signs of consciousness so if that's supposed to be reassuring, it's not.


Compared to chips, where would flies be? 1 bit microcontroller level? Where our brain is tops of course (latest generation AMD or Intel)


What does a "Hello World" for something like this look like? Is it a API, do I push a docker image to it or something? How do you interact with this sort of system?


There a Python interface. The API enables to send stimulations, measure action potentials and deliver dopamine in real-time. There are 2 videos that explains this in more details on: https://finalspark.com/neuroplatform/


ahh I didn't see the videos, thank you.


What does it feel like to be a real-life mad scientist?


Is the total mass of the organoids in your system greater than the mass of a single human brain?


Envelope calculation: 1 brain worth of neurons would make 10 million instances available for hire, and at 500 USD per instance would give monthly recurring revenue (MRR) at 5 billion USD.

Not too bad for a startup!


Honestly I see "rent your brain compute for money" as a real thing in the future.


I live that life now. It's a bit demeaning at times, but it beats physical hard labour.


No, it is way less. Consider we have about 10'000 neurons per organoid while our brain has about 100 billion.


I am one of FinalSpark's co-founder. You are right, this can be a concern. People who rent have the option to pay for exclusive access.


How hard is it to do something like this on your platform [0]? Are there any other real-world examples where people are using your platform to do something similar?

[0] https://www.youtube.com/watch?v=bEXefdbQDjw


If you talk about learning to play doom, I would say it is unrealistic at this point and still a topic of research, the purpose of the neuroplatform is precisely to find reliable ways to train neurons to perform a specific task.


What's the timeline for expanding the 8 electrodes (I assume that is the only way to get signals in and out)?


Well, we already have systems with 32 electrodes, and we are looking at alternative to increase this by several orders of magnitude. I hope we have something next year.


We are working on using living neurons in order to create the first bioprocessor. Neuron activity is available online on: https://finalspark.com/live/


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