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I assume this comment is trolling. But to be clear to readers, the link states psilocybin 50% increase in lifespan of human skin etc. not human lifespan.


"[...] extended the cellular lifespan of human skin and lung cells by more than 50%"

If we assume that the effect is the same for all types of cells, it follows that the life is extended by 50% (when keeping "all other factors" constant, as usual).


That's not a safe assumption.


It has to also down-regulate cells divisions, else it could be quite problematic.


The ideal business co-founder has to be strong in distribution AND eliciting product feedback. This is why the “MBA types” and ex-McKinsey consultants fare so poorly - they’re used to companies spending loads of money to hear what they think. As an early-stage startup founder, nobody gives a shit about your product and no one wants to hear what you think. Your job is to identify where demand is highest in the market and then turn that demand into dollars. They also need to be excellent communicators who understand or at least appreciate how much goes into building products.

For those reasons, the best business cofounders in my experience, are former salespeople (for b2b startups), demand generation marketers (for b2c), and product managers.


“Cecil - No civilization in history has ever considered ‘chief hydrological engineer’ a calling.”


Dear Operator With a Vision,

Please do more of the same thing that used to make me money and less of the thing that is risky.

Sincerely, Know-nothing Investor


“Between 2006, the peak of the previous housing bubble, and 2019, average home prices have increased just 13%, according to the S&P/Case-Shiller Home Price Index. In that same time period, the S&P 500 rose 125%. In other words, stocks did 10 times better than real estate”

I can’t take an article seriously when it purposefully ignores what’s happened in the last three years because it negates the point it’s trying to make.


Weasel words. Should have said "In other words, stocks did 10 times better than real estate... if you bought and sold at those exact times". It's easy to cherrypick these high and low marks to prove whatever point you need.


The article is dated 2019, so it's not a case of "purposefully ignores what's happened"; the last three years hadn't happened yet!


Taxicab companies don’t have to pay the Bay Area salaries of engineers, data scientists, MBAs, etc. nor do they have massive advertising and marketing overhead.


“Let me explain why crypto is bad by showing how it doesn’t fit neatly into the definitions of any of the monetary instruments that preceded it”


Also although I don't mention it in this article, I am the CTO of a competing fintech firm


The price of a catalytic converter is much higher. My friend’s catalytic converter was stolen from her late 2000s Accord, and her car was totaled as a result.


The title of this post in his newsletter was “Financial Devil’s Dictionary.” Wonder why he changed it.


Yea, that's loads better.


Why would this be illegal?


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