> while eventually tapering and getting them off the glp entirely as the final end goal
It's an honourable goal but the evidence isn't great for that
> You still have to improve diet and regularly exercise anyhow
You don't have to. Should though.
When the drugs are working as intended, you'll lose weight without 'trying' to improve your diet, exercise will speed up the weight loss, but isn't strictly necessary for it to "work". Encouraged, sure, but you'll get weight loss from the appetite suppression alone.
The 'high protein' advice is because a lot of glp1 consumers had poor diets to begin with, and they're catabolic drugs. Combine that with reduced appetite and you're at risk of insufficient protein consumption to maintain whatever muscle mass you started with.
> lacks the [...] bioavailability of real animal protein
I never understood this argument: what's the problem with consuming proportionately more to make up for the reduction?
I'm not rushing to demand IV tylenol because its oral bioavailability is only 80%-90%, which is around the "loss" we're talking for plant vs animal protein on average. And the ultraprocessing should improve plant's profile here.
Eating raw Miso a few times a month can move one's biome to get more plant protein digested per gram than even from egg whites. So the issue with protein is somewhat overhyped. The main potential shortfalls in the vegan diet are vitamins B-12, D & K.
>what's the problem with consuming proportionately more to make up for the reduction?
Because the macros suck. If you’re trying to hit certain protein / carb / fat ratios, eating more of the “protein” means eating a lot more carbs and fat too, which often isn’t the goal.
Your analogy is not accurate, it would be more like waking up in pain in the middle of the night after a bad injury, and taking t3s with codeine+ caffeine, and wanting more codeine without wanting the added caffeine.
if you have only fixed-ratio food options, sure, but otherwise, no.
> and taking t3s with codeine+ caffeine, and wanting more codeine without wanting the added caffeine.
that's what tylenol #4s are for, double the codeine, none the caffeine. Take half a t#4 and half of a regular standard tylenol = T#3 without the codeine.
On top of that, there seems to be a pervasive misconception of the effectiveness of plant vs animal-based protein on things like muscle growth. Older studies showed that plant-based proteins had lower digestibility scores via metrics like PDCAAS. In turn, people interpolated that muscle growth would be lower. Some early studies comparing the two protein sources on muscle synthesis didn't do gram-for-gram comparisons and that increased the misconception. Newer studies are showing that, if you match the protein amount at or above the 1-1.6 g/kg for muscle growth, you will get the same level of muscle growth.
I feel like it'll take another 5 years for this "bio-availability" myth to die out.
1. if you’re a natgas producing country with lots of farms (hi USA and Canada) , your mega farm is probably injecting ammonia directly into soil as its nitrogen source, not urea. Pdf pg10, labelled pg5: https://www.ers.usda.gov/sites/default/files/_laserfiche/pub...
80-90% of US nitrogen fertilization is ammonia (because it’s almost entirely nitrogen and the rest are bonded to heavier molecules than hydrogen).
And much of it gets applied in the fall, not spring
2. Nitrogen fertilizer varies by crop. Beans crops (soy, kidney beans, chickpeas) fixate their own nitrogen and have zero/minimal applied. Corn and grains, particularly the higher protein varieties need among the most applied.
3. If you like to eat farmed land animals, you’re going to have a bad time from high fertilizer prices. Of traditional edibles: cattle is going to be the worst impacted. Chicken the least. Pork is in the middle. https://www.pbs.org/wnet/peril-and-promise/2022/03/feed-conv...
I don't know if I agree with their conclusion on #3, beef is fed 90% alfalfa grass which is literally cheaper than dirt and fixates its own nitrogen. Yeah they eat more feed per pound of meat, but alfalfa is literally the cheapest and easiest crop to grow. Sow it, mow it, bail it, now you have good ground to plant grains in without artificial fertilizer next year. You only feed cows grains during their last month to finish them to increase marbling/fat content.
If you produce less beef, you grow less alfalfa, and you end up using more artificial fertilizer which might even raise grain prices.
For the foreseeable future, building enough nuclear for peak capacity is exceedingly expensive.
> None of the power plants ever do a "fast cold start"
Somewhere in each grid you will have “black start” capacity contracts, dunno if nuclear can fills this role (or if grids exclude nukes for one reason or another).
Plenty of peaker plants built with the intention of running double digit hours per year and therefore the tradeoff supports being largely “off” in between those calls. Batteries might fill that gap.
Some of the speed bumps-like techniques here in Sweden will do more than just be a bump, it will severely damage the tires if you don't slow down. Curbs that require the driver to make very tight turns for example can be made from fairly sharp stone with an clear edge. A SUV/pickup truck can speed over it, but the trip to the repair shop will make it less fun.
They added some square-like flower pots in the middle of a lovely road next to where I live in order to force drivers to make a double S turn. Those are made from sharp rust-painted steel, and most of the corners are now painted with other peoples car paint. The only way to make it through is to drive at walking speed, which basically everyone do.
That’s not how speed bumps work. You can drive over a speed bump in a sports car. It’s just uncomfortable and potentially damaging to do so at speed.
Most SUVs ride poorly compared to cars due to solid axles and huge unsprung weight. If you took a speed bump fast you would be very shaken up and possibly launch into the air or tip.
TLDR. Speed bumps aren’t “invisible” to SUVs unless you are in a competition pre-runner or a monster truck.
the SUV/pickup culture is bad enough here in the South but they place speedbumps aggressively all over the place here.
Like 4" tall ones with no curve so that it absolutely slams the shit out of your small car if you're doing anything over 3mph. And they place them like every 8 feet. If you're in the lifted trucks most people drive here you can't even tell.
But if you imported a lifted truck, or another daft US vehicle like the Cybertruck into another country it would probably not be roadworthy and the traffic and speed calming measures are more appropriate.
Bullbars used to be a trend in the UK, for example, until they were band in the late 90s/early 00s because they were fatal to pedestrians.
It's an honourable goal but the evidence isn't great for that
> You still have to improve diet and regularly exercise anyhow
You don't have to. Should though.
When the drugs are working as intended, you'll lose weight without 'trying' to improve your diet, exercise will speed up the weight loss, but isn't strictly necessary for it to "work". Encouraged, sure, but you'll get weight loss from the appetite suppression alone.
The 'high protein' advice is because a lot of glp1 consumers had poor diets to begin with, and they're catabolic drugs. Combine that with reduced appetite and you're at risk of insufficient protein consumption to maintain whatever muscle mass you started with.
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